Cannabidiol (CBD): Health Benefits, Side Effects and Uses
Cannabidiol (CBD) has been all over the media of late, and you’ll have even seen it advertised as a booster to your post-workout smoothie or morning coffee. So, what exactly is CBD? Why is it suddenly so popular?
Is cannabidiol different from marijuana?
CBD stands for cannabidiol. It is one of the most prevalent active ingredients of cannabis (marijuana). While CBD is an important component of medical marijuana, it’s derived directly from the hemp plant, which may be a cousin of the marijuana plant. While CBD may be a component of marijuana (one of the hundreds), by itself it doesn’t cause a “high.” consistent with a report from the planet Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health-related problems associated with the use of pure CBD.”
Is cannabidiol legal?
In India, CBS or any medical marijuana is not legal yet.
However, CBD is readily obtainable in most parts of the United States, though its exact legal status is unknown. All the states have laws regarding the legalization of CBD with varying restrictions, and while the federal still consider CBD within the same class as marijuana, it doesn’t habitually enforce against it. Currently, many of us obtain CBD online without a medical cannabis license. The government’s position on CBD is confusing and depends partially on whether the CBD comes from hemp or marijuana.
How does CBD work?
CBD has been advertised for a good number of health issues, but the strongest scientific evidence is for its effectiveness in treating several childhood epilepsy syndromes, like Dravet syndrome and Lennox-Gastaut syndrome (LGS), which generally don’t respond to antiseizure medications.
In numerous studies, CBD was ready to reduce the number of seizures, and in some cases, it had been ready to stop them altogether. Videos of the consequences of CBD on these children and their seizures are readily available on the web for viewing, and that they are quite striking. Recently the FDA approved the primary ever cannabis-derived medicine for these conditions, Epidiolex, which contains CBD.
CBD is usually used to manage, if not cure anxiety, and for patients that suffer from the terror of insomnia, studies suggest that CBD may help with both falling asleep and staying asleep i.e., improving the quality and quantity of your sleep.
CBD may offer an option for treating different types of chronic pain. A study from the ECU Journal of Pain showed, using an animal model, CBD applied to the skin could help lower pain and inflammation thanks to arthritis. Another study has demonstrated the mechanism by which CBD inhibits inflammatory and nerve pains. These happen to be two of the most difficult sorts of chronic pains to treat. More study in humans is required during this area to substantiate the claims of CBD proponents about pain control.
Cannabidiol affects the brain. The exact cause of these effects is not clear. However, cannabidiol seems to stop the breakdown of a chemical within the brain that affects pain, mood, and mental function. Preventing the breakdown of this chemical and increasing its levels within the blood seems to scale back psychotic symptoms related to conditions like schizophrenia. Cannabidiol may additionally block a number of the psychoactive effects of delta-9-tetrahydrocannabinol (THC). Also, cannabidiol seems to reduce pain and anxiety.
Is cannabidiol safe?
Side effects of CBD include a sense of puking, fatigue, and irritability. CBD can increase the extent in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the precise same mechanism that grapefruit juice does. A significant safety concern with CBD is that it’s primarily marketed and sold as a supplement, not a medicine.
Currently, the FDA doesn’t regulate the security and purity of dietary supplements. So you can’t know needless to say that the merchandise you purchase has active ingredients at the dose listed on the label. Also, the merchandise may contain other (unknown) elements. We also don’t know the foremost effective therapeutic dose of CBD for any particular medical condition.
Health benefits of CBD:
A specific cannabidiol product (Epidiolex, GW Pharmaceuticals) has been shown to scale back seizures in adults and youngsters with various conditions that are linked with seizures. This product may be a prescription for treating seizures caused by Dravet syndrome or Lennox-Gastaut syndrome. It has also been shown to reduce seizures in people with tuberous sclerosis complex, Sturge-Weber syndrome, febrile infection-related epilepsy syndrome (FIRES), and specific genetic disorders that cause epileptic encephalopathy.
But it’s not approved for treating these other types of seizures. This product is usually taken in combination with conventional anti-seizure medicines. Some cannabidiol products that are made during a lab also are being studied for epilepsy. But research is restricted, and none of those products are approved as prescribed drugs.
2. Multiple sclerosis
A prescription-only nasal spray product (Sativex, GW Pharmaceuticals) containing both 9-delta-tetrahydrocannabinol (THC) and cannabidiol is effective for improving pain, muscle-tightness, and urination frequency in people with MS. This product used in over 25 countries outside of the United States. But there inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis when it used alone. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness, but not muscle spasms, tiredness, bladder control, mobility, or well-being and quality of life in patients with MS.
3. Bipolar disorder
Early reports show that taking cannabidiol does not improve manic episodes in people with bipolar disorders. But, now, new research suggests otherwise.
4. Crohn’s disease and diabetes
Early research shows that taking cannabidiol does not reduce disease activity in adults with Crohn disease or diabetes but new claims suggest otherwise.
Dystonia, a movement disorder marked by involuntary muscle contractions. Early research suggests that taking cannabidiol daily for six weeks might improve dystonia by 20% to 50% in some people. Higher quality research needed to confirm this.
6. Graft vs host disease
Graft-versus-host disease is a complication that can occur after a bone marrow transplant. In people with this condition, donor cells attack the person’s cells. Early research shows that taking cannabidiol daily starting 7 days before bone marrow transplant and continuing for 30 days after transplant can extend the time it takes for a person to develop GVHD
7. Multiple Sclerosis
There is inconsistent evidence on the effectiveness of cannabidiol for symptoms of MS. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness in people with MS. However, it does not appear to improve muscle spasms, tiredness, bladder control, the ability to move around, or well-being and quality of life.
8. Withdrawal from heroin, morphine, codeine
Early research shows that taking cannabidiol for 3 days reduces cravings and anxiety in people with heroin use disorder that are not using heroin or any other opioid drugs.
Research on the utilization of cannabidiol for psychotic symptoms in people with schizophrenia is conflicting. Some early research suggests that taking cannabidiol fourfold daily for 4 weeks improves psychotic symptoms and could be as effective because of the antipsychotic medication amisulpride. However, other early research suggests that taking cannabidiol for 14 days isn’t beneficial. The conflicting results might be related to the cannabidiol dose used and the duration of treatment.
10. Parkinsons disease
Early research shows that taking a single dose of cannabidiol can reduce anxiety during public speaking in people with Parkinson’s disease. Other early research shows that consuming CBD every day for a month improves psychotic symptoms in people with Parkinson’s disease and psychosis.
11. Social anxiety disorder
Some early research shows that taking cannabidiol 300 mg daily does not improve anxiety during public speaking in people with a social anxiety disorder. But it might help with public speaking in people who don’t have a social anxiety disorder. It might also help with general social anxiety. Also, some research suggests that taking a higher dose (400-600 mg) may improve anxiety associated with a public speaking or medical imaging testing.
12. Quitting smoking
Early research suggests that inhaling cannabidiol with an inhaler for one week might reduce the number of cigarettes smoked by about 40% compared to baseline.
Side effects of CBD:
When taken orally: Cannabidiol is possibly safe when taken by mouth or sprayed under the tongue appropriately. Cannabidiol in doses of up to 300 mg daily taken orally safely for up to six months. Higher doses of 1200-1500 mg daily taken orally safely for up to 4 weeks. A prescription cannabidiol product (Epidiolex) approved to taken orally in doses of up to 10-20 mg/kg daily. Cannabidiol sprays that applied under the tongue utilized in doses of two .5 mg for up to 2 weeks.
Some reported side effects of cannabidiol include xerostomia, low vital sign, lightheadedness, and drowsiness. Signs of liver injury have also been reported in some patients, but this is less common.
1. Pregnancy and breast-feeding
Cannabidiol is POSSIBLY UNSAFE to use if you are pregnant or breastfeeding. Cannabidiol products often contaminated with other ingredients that will be harmful to the fetus or infant. Stay on the safe side and avoid use.
When applied to the skin: There isn’t enough reliable information to know if cannabidiol is safe or what the side effects might be.
A prescription cannabidiol product (Epidiolex) is POSSIBLY SAFE when taken orally daily. The most common dose used is 10 mg/kg daily. Higher doses of 15-20 mg/kg daily may be used in some children, but these higher doses are more likely to cause side effects. This product approved for use in certain children 2 years of age and older but has been used in children as young as 1 year of age.
3. Parkinson’s disease
Some early research suggests that taking high doses of cannabidiol might make muscle movement and tremors worse in people with Parkinson’s disease.
Liver disease: People with liver disease may need to use lower doses of cannabidiol compared to healthy patients.
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such CBD may be a cure-all for cancer, which it’s not. We need more research but CBD may be proving to be an option for managing anxiety, insomnia, and chronic pain.
Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses. Since CBD is currently is usually available as an unregulated supplement, it’s difficult to understand exactly what you are getting. If you opt to undertake CBD, talk together with your doctor. If for no other reason than to form sure it won’t affect other medications you’re taking.
We hope this article helped you to know about Cannabidiol (CBD): Health Benefits, Side Effects, Uses. You may also want to see our guide on What is crab walk exercise, and benefits of crab walking, and How To Maintain Hygiene In Intimate Area.